Summary

Name FHOD1
Full Name FH1/FH2 domain-containing protein 1
Synonyms Formin homolog overexpressed in spleen 1, FHOS, Formin homology 2 domain-containing protein 1 | FHOS, FHOS1
Primary ID Q9Y613
Links - -
Type protein
Relations 5
Function Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation FHOD1 0.317
Publications: 3 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation FHOD1 0.361
Publications: 2 Organism: Homo Sapiens
Tissue: Muscle, Smooth Muscle