+ |
EIF4E2 | form complex
binding
|
EIF4E2/GIGYF1 complex |
0.627 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261010 |
|
|
Homo sapiens |
|
pmid |
sentence |
30917308 |
4EHP forms complexes with the GYF domain-containing proteins GIGYF1 and GIGYF2, which are critical for this translational repression |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
EIF4E2/GIGYF1 complex | down-regulates
|
Protein_synthesis |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261012 |
|
|
Homo sapiens |
|
pmid |
sentence |
30917308 |
4EHP forms complexes with the GYF domain-containing proteins GIGYF1 and GIGYF2, which are critical for this translational repression |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
ZFP36 | up-regulates activity
relocalization
|
EIF4E2/GIGYF1 complex |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261014 |
|
|
Homo sapiens |
|
pmid |
sentence |
30917308 |
A key factor in this regulation is tristetraprolin (TTP), an RNA-binding protein (RBP) that recruits RNA-destabilizing factors and the translation inhibitory complex 4EHP-GIGYF1/2 to AU-rich element (ARE)-containing mRNAs |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
GIGYF1 | form complex
binding
|
EIF4E2/GIGYF1 complex |
0.627 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261011 |
|
|
Homo sapiens |
|
pmid |
sentence |
30917308 |
4EHP forms complexes with the GYF domain-containing proteins GIGYF1 and GIGYF2, which are critical for this translational repression |
|
Publications: |
1 |
Organism: |
Homo Sapiens |