| + |
ABCC8 | form complex 
binding
|
KATP channel |
0.644 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262056 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28842488 |
ATP-sensitive K+ (KATP) channels, found throughout the body, are generated as octameric complexes consisting of four pore-forming Kir6.1 or Kir6.2 subunits with four regulatory sulfonylurea receptor (SUR1 or SUR2) subunits. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
KCNJ11 | form complex
binding
|
KATP channel |
0.654 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262055 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28842488 |
ATP-sensitive K+ (KATP) channels, found throughout the body, are generated as octameric complexes consisting of four pore-forming Kir6.1 or Kir6.2 subunits with four regulatory sulfonylurea receptor (SUR1 or SUR2) subunits. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
KCNJ8 | form complex
binding
|
KATP channel |
0.646 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262054 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28842488 |
ATP-sensitive K+ (KATP) channels, found throughout the body, are generated as octameric complexes consisting of four pore-forming Kir6.1 or Kir6.2 subunits with four regulatory sulfonylurea receptor (SUR1 or SUR2) subunits. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
KATP channel | down-regulates quantity 
relocalization
|
calcium(2+) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-278148 |
|
|
Homo sapiens |
Pancreatic Beta Cell |
| pmid |
sentence |
| 35065096 |
Activated PKA and EPAC enhance insulin granular exocytosis by insulin granular priming and phosphorylates sulfonylurea receptor (SUR1) KATP channel subunit and thereby closes KATP-channels in the plasma membrane [13,43,82], leading to membrane depolarization, and opening of the voltage gated Ca2+-channels. This leads to an increased influx of extracellular Ca2+, which triggers fusion of intracellular insulin-containing granules with the plasma membrane and thereby insulin secretion. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ABCC9 | form complex
binding
|
KATP channel |
0.623 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262057 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28842488 |
ATP-sensitive K+ (KATP) channels, found throughout the body, are generated as octameric complexes consisting of four pore-forming Kir6.1 or Kir6.2 subunits with four regulatory sulfonylurea receptor (SUR1 or SUR2) subunits. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
KATP channel | up-regulates quantity 
relocalization
|
potassium(1+) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262053 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28842488 |
ATP-sensitive K+ (KATP) channels, found throughout the body, are generated as octameric complexes consisting of four pore-forming Kir6.1 or Kir6.2 subunits with four regulatory sulfonylurea receptor (SUR1 or SUR2) subunits. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
KATP channel