| + |
SMDT1 | form complex 
binding
|
MCU_MICU2_variant |
0.619 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270875 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32315830 |
MCU is a Ca2+-selective channel that mediates mitochondrial Ca2+ influx. The human channel contains tetrameric pore-forming MCU, regulatory subunits MICU1/2, and EMRE that is required both for channel function and MICU1/2-mediated Ca2+ regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MCU | form complex
binding
|
MCU_MICU2_variant |
0.698 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270874 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32315830 |
MCU is a Ca2+-selective channel that mediates mitochondrial Ca2+ influx. The human channel contains tetrameric pore-forming MCU, regulatory subunits MICU1/2, and EMRE that is required both for channel function and MICU1/2-mediated Ca2+ regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MICU1 | form complex
binding
|
MCU_MICU2_variant |
0.678 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270876 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32315830 |
MCU is a Ca2+-selective channel that mediates mitochondrial Ca2+ influx. The human channel contains tetrameric pore-forming MCU, regulatory subunits MICU1/2, and EMRE that is required both for channel function and MICU1/2-mediated Ca2+ regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MICU2 | form complex
binding
|
MCU_MICU2_variant |
0.645 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270877 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32315830 |
MCU is a Ca2+-selective channel that mediates mitochondrial Ca2+ influx. The human channel contains tetrameric pore-forming MCU, regulatory subunits MICU1/2, and EMRE that is required both for channel function and MICU1/2-mediated Ca2+ regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MCU_MICU2_variant | up-regulates quantity 
relocalization
|
calcium(2+) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270878 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 32315830 |
MCU is a Ca2+-selective channel that mediates mitochondrial Ca2+ influx. The human channel contains tetrameric pore-forming MCU, regulatory subunits MICU1/2, and EMRE that is required both for channel function and MICU1/2-mediated Ca2+ regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
MCU_MICU2_variant
CPX-5961