| + |
CyclinA2/CDK18 | down-regulates quantity by destabilization 
phosphorylation
|
AQP2 |
0.263 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-273438 |
Ser261 |
RQSVELHsPQSLPRG |
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 32164329 |
CDK18 controls AQP2 through phosphorylation at serine 261 and STUB1-mediated ubiquitination. |We had previously observed that a decrease in the phosphorylation of AQP2 at S261 is associated with a decrease in its poly-ubiquitination and an increase in its abundance |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CDK18 | form complex 
binding
|
CyclinA2/CDK18 |
0.401 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-273436 |
|
|
|
|
| pmid |
sentence |
| 33781185 |
PCTAIRE kinases (PCTKs) are a CDK subfamily, characterized by serine to cysteine mutation in the consensus PSTAIRE motif, involved in binding to the cyclin. One member of this class is PCTK3, which has two isoforms (a and b) and is also known as CDK18. After being activated by cyclin A2 or phosphorylation at Ser12 by PKA, PCTK3 can perform several functions. |
|
| Publications: |
1 |
| + |
CCNA2 | form complex
binding
|
CyclinA2/CDK18 |
0.401 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-273437 |
|
|
|
|
| pmid |
sentence |
| 33781185 |
PCTAIRE kinases (PCTKs) are a CDK subfamily, characterized by serine to cysteine mutation in the consensus PSTAIRE motif, involved in binding to the cyclin. One member of this class is PCTK3, which has two isoforms (a and b) and is also known as CDK18. After being activated by cyclin A2 or phosphorylation at Ser12 by PKA, PCTK3 can perform several functions. |
|
| Publications: |
1 |
3.0
CyclinA2/CDK18