Relation Results

Summary

Name KAT6A/PML
Primary ID SIGNOR-C55
Type complex
Formed by KAT6A, PML
Relations 2

Viewer

Type: Score: Layout: SPV 
0.5210.521PMLKAT6A/PMLKAT6A

Relations

Regulator
Mechanism
target
score
+ form complex img/form-complex.png binding KAT6A/PML 0.521
Identifier Residue Sequence Organism Cell Line
SIGNOR-201489 Homo sapiens Leukemia Cell
pmid sentence
We show here that moz is an acetyltransferase of p53 at k120 and k382 and colocalizes with p53 in promyelocytic leukemia (pml) nuclear bodies following cellular stress. The moz-pml-p53 interaction enhances moz-mediated acetylation of p53, and this ternary complex enhances p53-dependent p21 expression
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding KAT6A/PML 0.521
Identifier Residue Sequence Organism Cell Line
SIGNOR-201478 Homo sapiens Leukemia Cell
pmid sentence
We show here that moz is an acetyltransferase of p53 at k120 and k382 and colocalizes with p53 in promyelocytic leukemia (pml) nuclear bodies following cellular stress. The moz-pml-p53 interaction enhances moz-mediated acetylation of p53, and this ternary complex enhances p53-dependent p21 expression
Publications: 1 Organism: Homo Sapiens
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