3.0
Summary
| Name |  KAT6AView Modifications |
| Full Name | Histone acetyltransferase KAT6A |
| Synonyms | MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3, MYST-3, Monocytic leukemia zinc finger protein, Runt-related transcription factor-binding protein 2, Zinc finger protein 220 | MOZ, MYST3, RUNXBP2, ZNF220 |
| Primary ID | Q92794 |
| Links |  -  -  |
| Type | protein |
| Relations | 7 |
| Function | Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | KAT6A | up-regulates 
acetylation
|
TP53 | 0.657 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | KAT6A | form complex 
binding
|
KAT6A/KAT6B | 0.39 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | KAT6A | up-regulates
binding
|
RUNX2 | 0.313 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | KAT6A | up-regulates
binding
|
RUNX1 | 0.477 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | KAT6A | up-regulates quantity by expression
transcriptional regulation
|
CCL3 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | KAT6A | form complex
binding
|
KAT6A/PML | 0.502 |
| Publications: | 1 | Organism: | Homo Sapiens | |