| + |
DLG4 | up-regulates 
|
Postsynaptic density assembly |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264230 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 17243894 |
PSD-95 (the best-studied scaffold protein of the PSD, which binds to NR2 subunits of NMDA receptors) was found to be highly abundant in the adult forebrain PSD |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Glutamatergic synapse |
| + |
SHANK1 | up-regulates
|
Postsynaptic density assembly |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264605 |
|
|
Homo sapiens |
Neuron |
| pmid |
sentence |
| 28179641 |
SHANK proteins are ‘master’ scaffolding proteins that tether and organize intermediate scaffolding proteins. They are located at excitatory synapses, where they are crucial for proper synaptic development and function. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Glutamatergic synapse |
| + |
SHANK3 | up-regulates
|
Postsynaptic density assembly |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264607 |
|
|
Homo sapiens |
Neuron |
| pmid |
sentence |
| 28179641 |
SHANK proteins are ‘master’ scaffolding proteins that tether and organize intermediate scaffolding proteins. They are located at excitatory synapses, where they are crucial for proper synaptic development and function. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Glutamatergic synapse |
| + |
SHANK2 | up-regulates
|
Postsynaptic density assembly |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264606 |
|
|
Homo sapiens |
Neuron |
| pmid |
sentence |
| 28179641 |
SHANK proteins are ‘master’ scaffolding proteins that tether and organize intermediate scaffolding proteins. They are located at excitatory synapses, where they are crucial for proper synaptic development and function. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ANKS1B | up-regulates
|
Postsynaptic density assembly |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264226 |
|
|
Homo sapiens |
Neuron |
| pmid |
sentence |
| 26356309 |
AIDA-1 is highly enriched in postsynaptic density (PSD) fractions and is considered a major component of the PSD complex. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Glutamatergic synapse |
| + |
PKA | up-regulates
|
Postsynaptic density assembly |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264960 |
|
|
Homo sapiens |
Neuron |
| pmid |
sentence |
| 23125836 |
PKA is activated by Group I mGluRs in ACC neurons. The cAMP signaling pathway contributes to the activity-dependent synaptic plasticity in the anterior cingulate cortex |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Anterior Cingulate Cortex |
| Pathways: | Glutamatergic synapse, Oxytocin signaling |
3.0
Postsynaptic density assembly