Summary
Name | ![]() |
Primary ID | SIGNOR-PH234 |
Type | phenotype |
Description | Ferroptosis is defined as an iron-dependent, nonapoptotic form of cell death characterized by lipid peroxidation resulting from disturbances in the intracellular microenvironment, particularly under conditions of glutathione insufficiency. |
Relations | 2 |
Pathways | Ferroptosis in PDAC |
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Relations
Regulator | Mechanism | target | score ℹ | |
---|---|---|---|---|
+ | ACSL4 | up-regulates ![]() |
Ferroptosis | |
Publications: | 1 | Organism: | Homo Sapiens | |
+ | HMGCS1 | down-regulates ![]() |
Ferroptosis | |
Publications: | 1 | Organism: | Homo Sapiens | |