Summary

Name Ferroptosis
Primary ID SIGNOR-PH234
Type phenotype
Description Ferroptosis is defined as an iron-dependent, nonapoptotic form of cell death characterized by lipid peroxidation resulting from disturbances in the intracellular microenvironment, particularly under conditions of glutathione insufficiency.
Relations 3
Pathways Ferroptosis in PDAC

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Relations

Regulator Mechanism target score ℹ
+ ACSL4up-regulates img/indirect-activation.png Ferroptosis 0.7
Publications: 1 Organism: Homo Sapiens
+ Lipid peroxidationup-regulates img/direct-activation.png Ferroptosis 0.7
Publications: 1 Organism: Homo Sapiens
+ HMGCS1down-regulates img/indirect_inhibition.png Ferroptosis 0.7
Publications: 1 Organism: Homo Sapiens