| + |
PAX2 | up-regulates activity 
|
Urogenital_tract |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-252301 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 8575306 |
Pax-2 is required for multiple steps during the differentiation of intermediate mesoderm. In addition, Pax-2 mouse mutants provide an animal model for human hereditary kidney diseases. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| Pathways: | Focal segmental glomerulosclerosis |
| + |
WT1 | up-regulates activity
|
Urogenital_tract |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-252302 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 10101119 |
The Wilms' Tumour gene WT1 has important functions during development. Knock-out mice were shown to have defects in the urogenital system and to die at embryonic day E13.5, probably due to heart failure. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| Pathways: | Focal segmental glomerulosclerosis |
4.0
Urogenital_tract