Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-255886 |
|
|
Homo sapiens |
|
pmid |
sentence |
23132946 |
We then showed that ectopic expression of MLL fusion genes in both human and mouse normal hematopoietic stem/progenitor cells could significantly down-regulate endogenous expression of miR-495 and that the depletion of MLL fusions resulted in the up-regulation of miR-495. Thus, our data suggest that there is an MLL-fusion–mediated negative regulation of the production of miR-495 in hematopoietic cells. |
|