Relation Results

Summary

Name QRICH1
Full Name Transcriptional regulator QRICH1
Synonyms Glutamine-rich protein 1 |
Primary ID Q2TAL8
Links - -
Type protein
Relations 14
Function Transcriptional regulator that acts as a mediator of the integrated stress response (ISR) through transcriptional control of protein homeostasis under ...
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0.20.20.20.20.20.20.20.70.20.20.20.20.20.7QRICH1VARS2GARS1FARSBVARS1FARS2IARS1YARS2ER stressTARS2EARS2WARS1WARS2YARS1Cell_death

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Relations
Regulator
Mechanism
target
score ℹ
+ QRICH1up-regulates quantity by expression img/direct-activation.png transcriptional regulation VARS2 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269409 Homo sapiens
pmid sentence
QRICH1 promotes the expression of translation-related genes. our combined ChIP-seq and RNA-seq analyses identified that QRICH1 and ATF4 were enriched at the promoters of these specific tRNA synthetases, and that ER stress positively regulated their transcription (Fig. 4I). Together, these findings suggest that QRICH1 and ATF4 modulate tRNA metabolic processes to promote secreted protein synthesis during ER stress.
Publications: 1 Organism: Homo Sapiens
+ QRICH1up-regulates quantity by expression img/direct-activation.png transcriptional regulation GARS1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269405 Homo sapiens
pmid sentence
QRICH1 promotes the expression of translation-related genes. our combined ChIP-seq and RNA-seq analyses identified that QRICH1 and ATF4 were enriched at the promoters of these specific tRNA synthetases, and that ER stress positively regulated their transcription (Fig. 4I). Together, these findings suggest that QRICH1 and ATF4 modulate tRNA metabolic processes to promote secreted protein synthesis during ER stress.
Publications: 1 Organism: Homo Sapiens
+ QRICH1up-regulates quantity by expression img/direct-activation.png transcriptional regulation FARSB 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269404 Homo sapiens
pmid sentence
QRICH1 promotes the expression of translation-related genes. our combined ChIP-seq and RNA-seq analyses identified that QRICH1 and ATF4 were enriched at the promoters of these specific tRNA synthetases, and that ER stress positively regulated their transcription (Fig. 4I). Together, these findings suggest that QRICH1 and ATF4 modulate tRNA metabolic processes to promote secreted protein synthesis during ER stress.
Publications: 1 Organism: Homo Sapiens
+ QRICH1up-regulates quantity by expression img/direct-activation.png transcriptional regulation VARS1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269408 Homo sapiens
pmid sentence
QRICH1 promotes the expression of translation-related genes. our combined ChIP-seq and RNA-seq analyses identified that QRICH1 and ATF4 were enriched at the promoters of these specific tRNA synthetases, and that ER stress positively regulated their transcription (Fig. 4I). Together, these findings suggest that QRICH1 and ATF4 modulate tRNA metabolic processes to promote secreted protein synthesis during ER stress.
Publications: 1 Organism: Homo Sapiens
+ QRICH1up-regulates quantity by expression img/direct-activation.png transcriptional regulation FARS2 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269403 Homo sapiens
pmid sentence
QRICH1 promotes the expression of translation-related genes. our combined ChIP-seq and RNA-seq analyses identified that QRICH1 and ATF4 were enriched at the promoters of these specific tRNA synthetases, and that ER stress positively regulated their transcription (Fig. 4I). Together, these findings suggest that QRICH1 and ATF4 modulate tRNA metabolic processes to promote secreted protein synthesis during ER stress.
Publications: 1 Organism: Homo Sapiens
+ QRICH1up-regulates quantity by expression img/direct-activation.png transcriptional regulation IARS1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269406 Homo sapiens
pmid sentence
QRICH1 promotes the expression of translation-related genes. our combined ChIP-seq and RNA-seq analyses identified that QRICH1 and ATF4 were enriched at the promoters of these specific tRNA synthetases, and that ER stress positively regulated their transcription (Fig. 4I). Together, these findings suggest that QRICH1 and ATF4 modulate tRNA metabolic processes to promote secreted protein synthesis during ER stress.
Publications: 1 Organism: Homo Sapiens
+ QRICH1up-regulates quantity by expression img/direct-activation.png transcriptional regulation YARS2 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269413 Homo sapiens
pmid sentence
QRICH1 promotes the expression of translation-related genes. our combined ChIP-seq and RNA-seq analyses identified that QRICH1 and ATF4 were enriched at the promoters of these specific tRNA synthetases, and that ER stress positively regulated their transcription (Fig. 4I). Together, these findings suggest that QRICH1 and ATF4 modulate tRNA metabolic processes to promote secreted protein synthesis during ER stress.
Publications: 1 Organism: Homo Sapiens
+ ER stressup-regulates img/indirect-activation.png QRICH1 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-269398 Homo sapiens
pmid sentence
QRICH1 promotes cell death under ER stress
Publications: 1 Organism: Homo Sapiens
+ QRICH1up-regulates quantity by expression img/direct-activation.png transcriptional regulation TARS2 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269407 Homo sapiens
pmid sentence
QRICH1 promotes the expression of translation-related genes. our combined ChIP-seq and RNA-seq analyses identified that QRICH1 and ATF4 were enriched at the promoters of these specific tRNA synthetases, and that ER stress positively regulated their transcription (Fig. 4I). Together, these findings suggest that QRICH1 and ATF4 modulate tRNA metabolic processes to promote secreted protein synthesis during ER stress.
Publications: 1 Organism: Homo Sapiens
+ QRICH1up-regulates quantity by expression img/direct-activation.png transcriptional regulation EARS2 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269402 Homo sapiens
pmid sentence
QRICH1 promotes the expression of translation-related genes. our combined ChIP-seq and RNA-seq analyses identified that QRICH1 and ATF4 were enriched at the promoters of these specific tRNA synthetases, and that ER stress positively regulated their transcription (Fig. 4I). Together, these findings suggest that QRICH1 and ATF4 modulate tRNA metabolic processes to promote secreted protein synthesis during ER stress.
Publications: 1 Organism: Homo Sapiens
+ QRICH1up-regulates quantity by expression img/direct-activation.png transcriptional regulation WARS1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269410 Homo sapiens
pmid sentence
QRICH1 promotes the expression of translation-related genes. our combined ChIP-seq and RNA-seq analyses identified that QRICH1 and ATF4 were enriched at the promoters of these specific tRNA synthetases, and that ER stress positively regulated their transcription (Fig. 4I). Together, these findings suggest that QRICH1 and ATF4 modulate tRNA metabolic processes to promote secreted protein synthesis during ER stress.
Publications: 1 Organism: Homo Sapiens
+ QRICH1up-regulates quantity by expression img/direct-activation.png transcriptional regulation WARS2 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269411 Homo sapiens
pmid sentence
QRICH1 promotes the expression of translation-related genes. our combined ChIP-seq and RNA-seq analyses identified that QRICH1 and ATF4 were enriched at the promoters of these specific tRNA synthetases, and that ER stress positively regulated their transcription (Fig. 4I). Together, these findings suggest that QRICH1 and ATF4 modulate tRNA metabolic processes to promote secreted protein synthesis during ER stress.
Publications: 1 Organism: Homo Sapiens
+ QRICH1up-regulates quantity by expression img/direct-activation.png transcriptional regulation YARS1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269412 Homo sapiens
pmid sentence
QRICH1 promotes the expression of translation-related genes. our combined ChIP-seq and RNA-seq analyses identified that QRICH1 and ATF4 were enriched at the promoters of these specific tRNA synthetases, and that ER stress positively regulated their transcription (Fig. 4I). Together, these findings suggest that QRICH1 and ATF4 modulate tRNA metabolic processes to promote secreted protein synthesis during ER stress.
Publications: 1 Organism: Homo Sapiens
+ QRICH1up-regulates img/indirect-activation.png Cell_death 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-269399 Homo sapiens
pmid sentence
QRICH1 promotes cell death and its translation is upregulated by the PERK-eIF2α axis under ER stress.
Publications: 1 Organism: Homo Sapiens
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