| + |
RBX1 | form complex 
binding
|
BAF250b E3 ligase |
0.599 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271439 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 20086098 |
In the present work, we show that BAF250 associates with elongin C (Elo C), cullin 2 (Cul2), and Roc1 to form an E3 ubiquitin ligase. BAF250 forms an E3 ubiquitin ligase with Elo B/C, Cul2, and Roc1 that targets histone H2B. H2B-Ub has been shown to be required for transcriptional activation in vitro |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CUL2 | form complex
binding
|
BAF250b E3 ligase |
0.61 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271440 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 20086098 |
In the present work, we show that BAF250 associates with elongin C (Elo C), cullin 2 (Cul2), and Roc1 to form an E3 ubiquitin ligase. BAF250 forms an E3 ubiquitin ligase with Elo B/C, Cul2, and Roc1 that targets histone H2B. H2B-Ub has been shown to be required for transcriptional activation in vitro |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
BAF250b E3 ligase | down-regulates activity 
ubiquitination
|
Histone H2B |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271441 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 20086098 |
In the present work, we show that BAF250 associates with elongin C (Elo C), cullin 2 (Cul2), and Roc1 to form an E3 ubiquitin ligase. BAF250 forms an E3 ubiquitin ligase with Elo B/C, Cul2, and Roc1 that targets histone H2B. H2B-Ub has been shown to be required for transcriptional activation in vitro |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ARID1B | form complex
binding
|
BAF250b E3 ligase |
0.342 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271437 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 20086098 |
In the present work, we show that BAF250 associates with elongin C (Elo C), cullin 2 (Cul2), and Roc1 to form an E3 ubiquitin ligase. BAF250 forms an E3 ubiquitin ligase with Elo B/C, Cul2, and Roc1 that targets histone H2B. H2B-Ub has been shown to be required for transcriptional activation in vitro |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ELOC | form complex
binding
|
BAF250b E3 ligase |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271438 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 20086098 |
In the present work, we show that BAF250 associates with elongin C (Elo C), cullin 2 (Cul2), and Roc1 to form an E3 ubiquitin ligase. BAF250 forms an E3 ubiquitin ligase with Elo B/C, Cul2, and Roc1 that targets histone H2B. H2B-Ub has been shown to be required for transcriptional activation in vitro |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
BAF250b E3 ligase