| + |
NEO1 | up-regulates 
|
Chemoattraction_of_axon |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268395 |
|
|
|
|
| pmid |
sentence |
| 17204444 |
Neogenin, a close relative of the axon guidance receptor Deleted in Colorectal Cancer (DCC), has been shown to be a receptor for members of the Netrin and Repulsive Guidance Molecule (RGM) families. While Netrin-1-Neogenin interactions result in a chemoattractive axon guidance response, the interaction between Neogenin and RGMa induces a chemorepulsive response. |
|
| Publications: |
1 |
| Pathways: | Axon guidance |
| + |
CAMK2A | up-regulates
|
Chemoattraction_of_axon |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268385 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15363394 |
In this study, we have identified CaMKII and CaN-PP1 as the downstream effectors of localized Ca2+ signals in mediating attractive and repulsive turning responses of growth cones, respectively. Local Ca2+ elevation activates CaMKII and CaN-PP1 for attraction and repulsion, respectively. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Axon guidance |
| + |
DCC | up-regulates
|
Chemoattraction_of_axon |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268163 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 25881791 |
DCC constitutively expresses on the axonal surface. Netrin-1-binding to DCC induces chemoattraction |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Nervous System |
| Pathways: | Axon guidance |
3.0
Chemoattraction_of_axon