T-Lymphocyte: IL6

Pathway ID: SIGNOR-TLymphIL6

Description: IL-6 is one of the most important cytokines involved in the pro-inflamatory response. IL-6 receptor activates two distinct signaling pathways: JAK signalling and ERK signalling. Both pathways control the activation of T-cells through the Th17 phenotype.

Curated by: Alessandro Palma

13 Seed Entities

Organism:
Name Primary ID
IL17A Q16552
IL6R P08887
SMAD2/STAT3/EP300 SIGNOR-C203
FOXP3 Q9BZS1
Th17 SIGNOR-PH94
IL6ST P40189
SMAD2 Q15796
RORC P51449
EP300 Q09472
JAK1 P23458
ERK1/2 SIGNOR-PF1
STAT3 P40763
IL6 P05231