| + |
uridine | up-regulates quantity 
precursor of
|
uridine 5'-monophosphate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275856 |
|
|
|
|
| pmid |
sentence |
| 11306702 |
Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases.|We have cloned the cDNA of two human UCKs. The approximately 30-kDa proteins, named UCK1 and UCK2, were expressed in Escherichia coli and shown to catalyze the phosphorylation of Urd and Cyd. The enzymes did not phosphorylate deoxyribonucleosides or purine ribonucleosides. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280596 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35583288 |
Uridine-cytidine kinase like-1 (UCKL-1) is a largely uncharacterized protein with high sequence similarity to other uridine-cytidine kinases (UCKs). UCKs play an important role in the pyrimidine salvage pathway, catalyzing the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280604 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27239701 |
Uridine-cytidine kinase (UCK) is a pyrimidine ribonucleoside kinase that catalyses the first step of the pyrimidine salvage pathway, the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280612 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27239701 |
Uridine-cytidine kinase (UCK) is a pyrimidine ribonucleoside kinase that catalyses the first step of the pyrimidine salvage pathway, the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Publications: |
4 |
Organism: |
, Homo Sapiens |
| + |
UCKL1 | down-regulates quantity 
chemical modification
|
uridine |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280594 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35583288 |
Uridine-cytidine kinase like-1 (UCKL-1) is a largely uncharacterized protein with high sequence similarity to other uridine-cytidine kinases (UCKs). UCKs play an important role in the pyrimidine salvage pathway, catalyzing the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UCK1 | down-regulates quantity
chemical modification
|
uridine |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280602 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27239701 |
Uridine-cytidine kinase (UCK) is a pyrimidine ribonucleoside kinase that catalyses the first step of the pyrimidine salvage pathway, the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UCK2 | down-regulates quantity
chemical modification
|
uridine |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280610 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27239701 |
Uridine-cytidine kinase (UCK) is a pyrimidine ribonucleoside kinase that catalyses the first step of the pyrimidine salvage pathway, the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UPP1 | up-regulates quantity
chemical modification
|
uridine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280527 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21855639 |
Uridine phosphorylase (UPP) catalyzes the reversible conversion of uridine to uracil and ribose-1-phosphate and plays an important pharmacological role in activating fluoropyrimidine nucleoside chemotherapeutic agents such as 5-fluorouracil and capecitabine. Most vertebrate animals, including humans, possess two homologs of this enzyme (UPP1 & UPP2), of which UPP1 has been more thoroughly studied and is better characterized |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
uracil | up-regulates quantity
precursor of
|
uridine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280528 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21855639 |
Uridine phosphorylase (UPP) catalyzes the reversible conversion of uridine to uracil and ribose-1-phosphate and plays an important pharmacological role in activating fluoropyrimidine nucleoside chemotherapeutic agents such as 5-fluorouracil and capecitabine. Most vertebrate animals, including humans, possess two homologs of this enzyme (UPP1 & UPP2), of which UPP1 has been more thoroughly studied and is better characterized |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280532 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21855639 |
Uridine phosphorylase (UPP) catalyzes the reversible conversion of uridine to uracil and ribose-1-phosphate and plays an important pharmacological role in activating fluoropyrimidine nucleoside chemotherapeutic agents such as 5-fluorouracil and capecitabine. Most vertebrate animals, including humans, possess two homologs of this enzyme (UPP1 & UPP2), of which UPP1 has been more thoroughly studied and is better characterized |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
UPP2 | up-regulates quantity
chemical modification
|
uridine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280531 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21855639 |
Uridine phosphorylase (UPP) catalyzes the reversible conversion of uridine to uracil and ribose-1-phosphate and plays an important pharmacological role in activating fluoropyrimidine nucleoside chemotherapeutic agents such as 5-fluorouracil and capecitabine. Most vertebrate animals, including humans, possess two homologs of this enzyme (UPP1 & UPP2), of which UPP1 has been more thoroughly studied and is better characterized |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
uridine