| + |
FAD(3-) | up-regulates quantity 
precursor of
|
FADH2(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280309 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20490924 |
VLCAD is a dimer of two identical subunits bound to the inner mitochondrial membrane (Fig. 1) and accepts long chain acyl-CoAs as substrate (Fig. 4a).The different ACADs catalyze the following reaction: acyl-CoA + FAD - trans-2-enoyl-CoA + FADH2 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280399 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21237683 |
Long-chain fatty acids are an important source of energy in muscle and heart where the acyl-CoA dehydrogenases (ACADs) participate in consecutive cycles of β-oxidation to generate acetyl-CoA and reducing equivalents for generating energy. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
ACADS | down-regulates quantity 
chemical modification
|
FAD(3-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280395 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21237683 |
Long-chain fatty acids are an important source of energy in muscle and heart where the acyl-CoA dehydrogenases (ACADs) participate in consecutive cycles of β-oxidation to generate acetyl-CoA and reducing equivalents for generating energy. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280415 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11134486 |
Short-chain acyl-CoA dehydrogenase (SCAD) (EC 1.3.99.2) is the first enzyme of the mitochondrial short-chain β-oxidation spiral catalyzing the dehydrogenation of C4 and C6 fatty acids |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
ACADVL | down-regulates quantity
chemical modification
|
FAD(3-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280305 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20490924 |
VLCAD is a dimer of two identical subunits bound to the inner mitochondrial membrane (Fig. 1) and accepts long chain acyl-CoAs as substrate (Fig. 4a).The different ACADs catalyze the following reaction: acyl-CoA + FAD - trans-2-enoyl-CoA + FADH2 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ACADL | down-regulates quantity
chemical modification
|
FAD(3-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280327 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18227065 |
Very-long-chain acyl-CoA dehydrogenase (VLCAD) is a member of the family of acyl-CoA dehydrogenases (ACADs). Very-long-chain acyl-CoA dehydrogenase (VLCAD)3 is one of five acyl-CoA dehydrogenases (ACADs) that catalyze the initial, rate-limiting step of mitochondrial fatty acid β-oxidation, with distinct but overlapping fatty acyl chain-length specificities.When myristoyl-CoA was added, the yellow enzyme solution turned colorless, indicating that the enzyme flavin was reduced by the substrate. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ACADM | down-regulates quantity
chemical modification
|
FAD(3-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280357 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 3035565 |
Medium-chain acyl-CoA dehydrogenase (MCAD; acyl-CoA: (acceptor) 2,3- oxidoreductase, EC 1.3.99.3) is one of three similar enzymes that catalyze the initial step of fatty acid beta-oxidation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FAD(3-) | form complex 
binding
|
ETF |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269469 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 33450351 |
Human ETF is nuclear encoded by two separate genes, ETFA and ETFB, respectively. After translation, the two subunits are imported to the mitochondrial matrix space and assemble into a heterodimer containing one FAD and one AMP as cofactors. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
FAD(3-)
