Summary

Name midostaurin
Synonyms 4'-N-benzoylstaurosporine (ChemIDplus), benzoylstaurosporine (ChemIDplus), CGP 41251 (ChemIDplus), CGP-41251 (ChemIDplus), midostaurin (ChemIDplus), PKC 412 (ChemIDplus), PKC412 (ChemIDplus)
IUPAC N-[(5S,6R,7R,9R)-6-methoxy-5-methyl-14-oxo-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-7-yl]-N-methylbenzamide
Formula C35H30N4O4
PRIMARY ID
(Read more)
CHEBI:63452
Type chemical
Relations 6
Pathways Acute Myeloid Leukemia, FLT3 in AML

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png chemical inhibition FLT3 0.8
Publications: 2 Organism: In Vitro
Pathways:Acute Myeloid Leukemia, FLT3 in AML
+ down-regulates activity img/direct_inhibition.png chemical inhibition KIT 0.8
Publications: 1 Organism: In Vitro
Pathways:Acute Myeloid Leukemia
+ down-regulates activity img/direct_inhibition.png chemical inhibition KDR 0.8
Publications: 1
+ down-regulates activity img/direct_inhibition.png chemical inhibition FGR 0.8
Publications: 1 Organism: In Vitro
+ down-regulates activity img/direct_inhibition.png chemical inhibition PRKCA 0.8
Publications: 1