Relation Results

Summary

Name LY294002
Synonyms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (ChemIDplus), 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (KEGG COMPOUND), LY 294002 (KEGG COMPOUND)
IUPAC 2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one
Formula C19H17NO3
PRIMARY ID
(Read more)		 CHEBI:65329
Type chemical
Relations 3

Viewer

Type: Score: Layout: SPV 
0.80.80.8LY294002PI3KPIK3R1PIK3C3

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Relations
Regulator
Mechanism
target
score ℹ
+ LY294002down-regulates img/direct_inhibition.png chemical inhibition PI3K 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-252647 Homo sapiens Myoblast
pmid sentence
Here we show that inhibition of pi3-k activity by the pharmacological agent ly294002 affects early processes of myoblast differentiation including the transcriptional activation of myogenin.
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle, Skeletal Muscle
+ LY294002down-regulates img/direct_inhibition.png chemical inhibition PIK3R1 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-79347 Homo sapiens Myoblast
pmid sentence
Here we show that inhibition of pi3-k activity by the pharmacological agent ly294002 affects early processes of myoblast differentiation including the transcriptional activation of myogenin.
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle, Skeletal Muscle
+ LY294002down-regulates img/direct_inhibition.png chemical inhibition PIK3C3 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-260731 Chlorocebus aethiops Vero Cell
pmid sentence
From these results, we conclude that LY294002 and wortmannin inhibit SARS pseudovirus entry by targeting PI4KB and that PI4KB is involved in SARS-CoV S-mediated entry into VeroE6 cells.
Publications: 1 Organism: Chlorocebus Aethiops
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