4.0
Summary
| Name |  linifanib
|
| Synonyms | 1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea (LINCS), ABT 869 (ChemIDplus), ABT-869 (ChemIDplus), ABT869 (ChEBI), linifanib (WHO MedNet), linifanib (WHO MedNet), linifanib (WHO MedNet), linifanibum (WHO MedNet), N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea (ChemIDplus) |
| IUPAC | |
| Formula | C21H18FN5O |
| PRIMARY ID (Read more) |
CHEBI:91435 |
| Type | chemical |
| Relations | 8 |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | linifanib | down-regulates activity 
chemical inhibition
|
CSF1R | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | linifanib | down-regulates activity
chemical inhibition
|
FLT4 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | linifanib | down-regulates activity
chemical inhibition
|
KDR | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | linifanib | down-regulates activity
chemical inhibition
|
FLT3 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | linifanib | down-regulates
chemical inhibition
|
PDGFRA | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | linifanib | down-regulates
chemical inhibition
|
KDR | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | linifanib | down-regulates
chemical inhibition
|
PDGFRB | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | linifanib | down-regulates activity
chemical inhibition
|
FLT1 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |