4.0
Summary
| Name |  RGS16View Modifications |
| Full Name | Regulator of G-protein signaling 16 |
| Synonyms | RGS16, A28-RGS14P, Retinal-specific RGS, RGS-r, hRGS-r, Retinally abundant regulator of G-protein signaling | RGSR |
| Primary ID | O15492 |
| Links |  -  -  |
| Type | protein |
| Relations | 6 |
| Function | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11602604, PubMed:18434541). Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | EGFR | up-regulates 
phosphorylation
|
RGS16 | 0.407 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | LYN | up-regulates activity
phosphorylation
|
RGS16 | 0.339 |
| Publications: | 1 | Organism: | In Vitro | |
| + | SRC | up-regulates
phosphorylation
|
RGS16 | 0.338 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | hsa-miR-181a-5p | down-regulates quantity by repression 
post transcriptional regulation
|
RGS16 | 0.4 |
| Publications: | 1 | Organism: | Homo Sapiens | |