Relation Results

Summary

Name MSI1
Full Name RNA-binding protein Musashi homolog 1
Synonyms Musashi-1
Primary ID O43347
Links - -
Type protein
Relations 3
Function RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds ...
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Type: Score: Layout: SPV 
0.4550.2870.269MSI1NUMBCCND1ERBB2

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Relations
Regulator
Mechanism
target
score ℹ
+ MSI1down-regulates img/direct_inhibition.png binding NUMB 0.455
Identifier Residue Sequence Organism Cell Line
SIGNOR-165617 Homo sapiens
pmid sentence
The study confirmed p21(cip1) and numb proteins as targets of musashi1, suggesting additionally p27(kip1) in cell-cycle regulation and jagged-1 in notch .
Publications: 1 Organism: Homo Sapiens
+ CCND1up-regulates quantity by expression img/indirect-activation.png transcriptional regulation MSI1 0.287
Identifier Residue Sequence Organism Cell Line
SIGNOR-165186 Homo sapiens
pmid sentence
We hypothesized that cyclin d1 may induce notch1 activity either by repressing numb or by inducing musashi 1 expression
Publications: 1 Organism: Homo Sapiens
+ ERBB2up-regulates quantity by expression img/indirect-activation.png transcriptional regulation MSI1 0.269
Identifier Residue Sequence Organism Cell Line
SIGNOR-165195 Homo sapiens
pmid sentence
We investigated the possibilities that erbb2 may regulate downstream mediators of notch1 signaling to induce musashi1 (which enhances notch1 signaling).
Publications: 1 Organism: Homo Sapiens
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