Summary

Name WIPF1
Full Name WAS/WASL-interacting protein family member 1
Synonyms Protein PRPL-2, Wiskott-Aldrich syndrome protein-interacting protein, WASP-interacting protein | WASPIP, WIP
Primary ID O43516
Links - -
Type protein
Relations 1
Function Plays a role in the reorganization of the actin cytoskeleton. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation. Plays a role in the formation of cell ruffles (By similarity). Plays an important role in the intracellular motility of vaccinia virus by functioning as an adapter for recruiting WASL to vaccinia virus.

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation WIPF1 0.40
Publications: 1 Organism: In Vitro