3.0
Summary
| Name |  WIPF1View Modifications |
| Full Name | WAS/WASL-interacting protein family member 1 |
| Synonyms | Protein PRPL-2, Wiskott-Aldrich syndrome protein-interacting protein, WASP-interacting protein | WASPIP, WIP |
| Primary ID | O43516 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Plays a role in the reorganization of the actin cytoskeleton. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation. Plays a role in the formation of cell ruffles (By similarity). Plays an important role in the intracellular motility of vaccinia virus by functioning as an adapter for recruiting WASL to vaccinia virus. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PRKCQ | up-regulates activity 
phosphorylation
|
WIPF1 | 0.328 |
| Publications: | 1 | Organism: | In Vitro | |
| + | WIPF1 | up-regulates 
|
Endocytosis | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | WIPF1 | up-regulates activity
binding
|
WASL | 0.931 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | WIPF1 | up-regulates
|
Early Endosome | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | FKBP15 | up-regulates activity
binding
|
WIPF1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |