Summary

Name APC2
Full Name Adenomatous polyposis coli protein 2
Synonyms Adenomatous polyposis coli protein-like, APC-like | APCL
Primary ID O95996
Links - -
Type protein
Relations 3
Function Stabilizes microtubules and may regulate actin fiber dynamics through the activation of Rho family GTPases (PubMed:25753423). May also function in Wnt signaling by promoting the rapid degradation of CTNNB1 (PubMed:10021369, PubMed:11691822, PubMed:9823329).

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Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png relocalization CTNNB1 0.34
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding AXIN1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GSK3B/Axin/APC 0.14
Publications: 1 Organism: Homo Sapiens