Relation Results

Summary

Name GAST
Full Name Gastrin [Cleaved into: Gastrin-71
Synonyms GAST_HUMAN | GAS
Primary ID P01350
Links - -
Type protein
Relations 3
Pathways GPCR_CRC
Function Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates s ...
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Type: Score: Layout: SPV 
0.2790.3460.782GASTSLC4A2EGR1CCKBR

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Relations
Regulator
Mechanism
target
score ℹ
+ GASTup-regulates quantity by expression img/indirect-activation.png transcriptional regulation SLC4A2 0.279
Identifier Residue Sequence Organism Cell Line
SIGNOR-254251 Homo sapiens
pmid sentence
Gastrin inhibited proliferation of colon cancer cells by suppressing expression of EGR1 and AE2 and by blocking ERK phosphorylation.
Publications: 1 Organism: Homo Sapiens
Tissue: Colon
+ GASTup-regulates quantity by expression img/indirect-activation.png transcriptional regulation EGR1 0.346
Identifier Residue Sequence Organism Cell Line
SIGNOR-254252 Homo sapiens
pmid sentence
Gastrin inhibited proliferation of colon cancer cells by suppressing expression of EGR1 and AE2 and by blocking ERK phosphorylation.
Publications: 1 Organism: Homo Sapiens
Tissue: Colon
+ GASTup-regulates img/direct-activation.png binding CCKBR 0.782
Identifier Residue Sequence Organism Cell Line
SIGNOR-66987 Homo sapiens
pmid sentence
A segment of five amino acids in the second extracellular loop of the cck-b receptor was shown to be essential for the high affinity of the natural peptide agonits, gastrin,
Publications: 1 Organism: Homo Sapiens
Tissue: Brain
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