Summary

Name PTPRF
Full Name Receptor-type tyrosine-protein phosphatase F
Synonyms Leukocyte common antigen related, LAR | LAR
Primary ID P10586
Links - -
Type protein
Relations 17
Function Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity.; FUNCTION

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png dephosphorylation AKT1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png dephosphorylation RET 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png dephosphorylation INSR 0.34
Publications: 8 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png dephosphorylation FYN 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Brain, Kidney
+ up-regulates img/direct-activation.png dephosphorylation DAPK1 0.14
Publications: 2 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png dephosphorylation FYN 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Brain, Kidney
+ up-regulates img/direct-activation.png dephosphorylation LCK 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Brain, Kidney
+ up-regulates activity img/direct-activation.png phosphorylation PTPRF 0.14
Publications: 1 Organism: Chlorocebus Aethiops
+ down-regulates img/direct_inhibition.png dephosphorylation PLCG1 0.14
Publications: 1 Organism: Homo Sapiens