| + |
YY1 | up-regulates quantity by expression 
transcriptional regulation
|
FCER1A |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254290 |
|
|
Homo sapiens |
KU-812 Cell |
| pmid |
sentence |
| 11971001 |
Transcriptional regulation of the gene-encoding human Fc epsilon RI alpha-chain was analyzed in detail. EMSA revealed that either YY1 or PU.1 bound to the region close to that recognized by Elf-1. The alpha-chain promoter activity was up-regulated approximately 2-fold by exogenously expressed YY1 or PU.1 and approximately 7-fold by GATA-1, respectively, in KU812 cells |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
GATA1 | up-regulates quantity by expression
transcriptional regulation
|
FCER1A |
0.319 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254288 |
|
|
Homo sapiens |
KU-812 Cell |
| pmid |
sentence |
| 11971001 |
Transcriptional regulation of the gene-encoding human Fc epsilon RI alpha-chain was analyzed in detail. EMSA revealed that either YY1 or PU.1 bound to the region close to that recognized by Elf-1. The alpha-chain promoter activity was up-regulated approximately 2-fold by exogenously expressed YY1 or PU.1 and approximately 7-fold by GATA-1, respectively, in KU812 cells |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ELF1 | down-regulates quantity by repression 
transcriptional regulation
|
FCER1A |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254287 |
|
|
Homo sapiens |
KU-812 Cell |
| pmid |
sentence |
| 11971001 |
Transcriptional regulation of the gene-encoding human Fc epsilon RI alpha-chain was analyzed in detail. EMSA revealed that either YY1 or PU.1 bound to the region close to that recognized by Elf-1|These up-regulating effects of PU.1 and YY1 with GATA-1 were inhibited by overexpression of Elf-1, indicating that Elf-1 serves as a repressor for the alpha-chain gene expression |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FCER1A | form complex 
binding
|
FCER1 |
0.667 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254959 |
|
|
Homo sapiens |
Mast Cell |
| pmid |
sentence |
| 16470226 |
FcepsilonRI is a tetrameric receptor that comprises an alpha-chain, which is responsible for binding IgE, as well as a beta-chain and a disulphide-linked gamma-chain homo dimer, which are responsible for initiating signalling. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SPI1 | up-regulates quantity by expression
transcriptional regulation
|
FCER1A |
0.28 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254289 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11971001 |
Transcriptional regulation of the gene-encoding human Fc epsilon RI alpha-chain was analyzed in detail. EMSA revealed that either YY1 or PU.1 bound to the region close to that recognized by Elf-1. The alpha-chain promoter activity was up-regulated approximately 2-fold by exogenously expressed YY1 or PU.1 and approximately 7-fold by GATA-1, respectively, in KU812 cells |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
FCER1A
- 
- 