3.0
Mast cell: FCERI
Pathway ID: SIGNOR-MastFCERI
Description: Mast-cell activation mediated by the high-affinity receptor for IgE (Fc epsilon RI) is considered to be an important event in the release of mediators by these cells. The degranulation is dependent on this signaling pathway, and involves SRC protein family, which associates with FCeR and leads to the degranulation process.
Curated by: Alessandro Palma
Description: Mast-cell activation mediated by the high-affinity receptor for IgE (Fc epsilon RI) is considered to be an important event in the release of mediators by these cells. The degranulation is dependent on this signaling pathway, and involves SRC protein family, which associates with FCeR and leads to the degranulation process.
Curated by: Alessandro Palma
10 Seed Entities
Organism: 
|
Name | Primary ID |
|---|---|
| SRC_kinase_family | SIGNOR-PF32 |
| Degranulation | SIGNOR-PH92 |
| FCER1 | SIGNOR-C200 |
| IL5 | P05113 |
| FCER1G | P30273 |
| FCER1G/FCER1G | SIGNOR-C199 |
| TNF | P01375 |
| MS4A2 | Q01362 |
| FCER1A | P12319 |
| IL6 | P05231 |