Summary

Name RAC2
Full Name Ras-related C3 botulinum toxin substrate 2
Synonyms GX, Small G protein, p21-Rac2
Primary ID P15153
Links - -
Type protein
Relations 4
Function Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.

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Relations

Regulator Mechanism target score ℹ
+ RAC2up-regulates img/direct-activation.png binding PAK1 0.773
Publications: 1 Organism: Homo Sapiens
+ SRGAP3down-regulates img/indirect_inhibition.png RAC2 0.533
Publications: 1 Organism: Homo Sapiens
+ RAP1GDS1up-regulates img/direct-activation.png binding RAC2 0.513
Publications: 1 Organism: Homo Sapiens
+ SH3RF1up-regulates img/direct-activation.png binding RAC2 0.266
Publications: 1 Organism: Homo Sapiens