3.0
Summary
| Name |  VCLView Modifications |
| Full Name | Vinculin |
| Synonyms | Metavinculin, MV |
| Primary ID | P18206 |
| Links |  -  -  |
| Type | protein |
| Relations | 6 |
| Function | Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PRKCA |
phosphorylation
|
VCL | 0.397 |
| Publications: | 2 | Organism: | In Vitro | |
| + | SRC | down-regulates activity 
phosphorylation
|
VCL | 0.754 |
| Publications: | 2 | Organism: | Chlorocebus Aethiops | |
| + | PTPRG | down-regulates activity
dephosphorylation
|
VCL | 0.2 |
| Publications: | 1 | Organism: | In Vitro | |
| + | ABL1 | up-regulates activity 
phosphorylation
|
VCL | |
| Publications: | 1 | Organism: | Homo Sapiens | |