Summary

Name ADSS2
Full Name Adenylosuccinate synthetase isozyme 2
Synonyms AMPSase 2, AdSS 2, Adenylosuccinate synthetase, acidic isozyme, Adenylosuccinate synthetase, liver isozyme, L-type adenylosuccinate synthetase, IMP--aspartate ligase 2 | ADSS2
Primary ID P30520
Links - -
Type protein
Relations 5
Pathways Aspartate and asparagine metabolism, Nucleotide Biosynthesis
Function Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

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Relations

Regulator Mechanism target score ℹ
+ ADSS2down-regulates quantity img/direct_inhibition.png chemical modification L-aspartate(1-) 0.8
Publications: 1 Organism: Homo Sapiens
Pathways:Aspartate and asparagine metabolism, Nucleotide Biosynthesis
+ ADSS2up-regulates quantity img/direct-activation.png chemical modification N(6)-(1,2-dicarboxylatoethyl)-AMP(4-) 0.8
Publications: 1 Organism: Homo Sapiens
Pathways:Nucleotide Biosynthesis
+ ADSS2down-regulates quantity img/direct_inhibition.png chemical modification IMP 0.8
Publications: 1 Organism: Homo Sapiens
Pathways:Nucleotide Biosynthesis
+ ADSS2up-regulates img/indirect-activation.png Nucleotide_synthesis 0.7
Publications: 1 Organism: Homo Sapiens
Pathways:Aspartate and asparagine metabolism
+ ADSS2up-regulates quantity img/direct-activation.png chemical modification GDP 0.8
Publications: 1 Organism: Homo Sapiens
Pathways:Nucleotide Biosynthesis