Summary

Name NTSR1
Full Name Neurotensin receptor type 1
Synonyms NT-R-1, NTR1, High-affinity levocabastine-insensitive neurotensin receptor, NTRH | NTRR
Primary ID P30989
Links - -
Type protein
Relations 7
Function G-protein coupled receptor for the tridecapeptide neurotensin (NTS) (PubMed:8381365, PubMed:21725197, PubMed:23140271). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis (PubMed:21725197).

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Relations

Regulator Mechanism target score ℹ
+ NTSR1up-regulates activity img/direct-activation.png binding GNAO1 0.275
Publications: 1 Organism: Cricetulus Longicaudatus
+ NTSR1up-regulates activity img/direct-activation.png binding GNAI1 0.268
Publications: 1 Organism: Cricetulus Longicaudatus
+ NTSR1up-regulates activity img/direct-activation.png binding GNAQ 0.467
Publications: 1 Organism: Cricetulus Longicaudatus
+ GRK5up-regulates activity img/direct-activation.png phosphorylation NTSR1 0.592
Publications: 1 Organism: Homo Sapiens
+ NTSR1up-regulates activity img/direct-activation.png binding GNA13 0.25
Publications: 1 Organism: Cricetulus Longicaudatus
+ GRK2up-regulates activity img/direct-activation.png phosphorylation NTSR1 0.2
Publications: 1 Organism: Homo Sapiens
+ NTSup-regulates img/direct-activation.png binding NTSR1 0.93
Publications: 1 Organism: Homo Sapiens
Tissue: Ovary