Summary

Name ADRA1A
Full Name Alpha-1A adrenergic receptor
Synonyms Alpha-1A adrenoreceptor, Alpha-1A adrenoceptor, Alpha-1C adrenergic receptor, Alpha-adrenergic receptor 1c | ADRA1C
Primary ID P35348
Links - -
Type protein
Relations 2
Inhibitors Silodosin; Bmy-7378
Function This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png chemical inhibition ADRA1A
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png chemical inhibition ADRA1A
Publications: 1 Organism: Homo Sapiens