| + |
PLCB1 | up-regulates 
binding
|
GNA11 |
0.624 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-17239 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 1322796 |
Plc-_1 stimulates hydrolysis of gq/11-bound gtp and acts as a gtpase-activating protein (gap) for its physiologic regulator, gq/11 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Thyroid Hormone Metabolism |
| + |
TRHR | up-regulates activity
binding
|
GNA11 |
0.486 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267201 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27515033 |
Binding of TRH to TRH-R1 receptor, which is coupled to Gq/11 protein, activates phospholipase C, mobilizes calcium and activates protein kinase C. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Thyroid Gland |
| Pathways: | Thyroid Hormone Metabolism |
| + |
AGTR1 | up-regulates activity
binding
|
GNA11 |
0.514 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-278125 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 20181817 |
The angiotensin II type 1 receptor (AT1 R) is a G q/11-coupled G protein-coupled receptor that is widely expressed in multiple tissues, including vascular smooth muscle cells, brain, and kidney. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
GNA11 | up-regulates activity
binding
|
PLCB1 |
0.624 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267203 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 27515033 |
TRH-R1 receptor, which is coupled to Gq/11 protein, activates phospholipase C, mobilizes calcium and activates protein kinase C. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Thyroid Hormone Metabolism |
| + |
ADRA1A | up-regulates activity
binding
|
GNA11 |
0.575 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-278121 |
|
|
Chlorocebus aethiops |
COS-7 Cell |
| pmid |
sentence |
| 1334487 |
In this report, we demonstrate that in transfected cos-7 cells Gal4 and Ga16, like Gaq and Ga11, can activate PIPLC j3l and that all three al-ARs, alA, alB and alC, can activate endogenous PI-PLC by coupling to Gaq or Ga11. |
|
| Publications: |
1 |
Organism: |
Chlorocebus Aethiops |
| + |
ADRA1B | up-regulates activity
binding
|
GNA11 |
0.662 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-278122 |
|
|
Chlorocebus aethiops |
COS-7 Cell |
| pmid |
sentence |
| 1334487 |
In this report, we demonstrate that in transfected cos-7 cells Gal4 and Ga16, like Gaq and Ga11, can activate PIPLC j3l and that all three al-ARs, alA, alB and alC, can activate endogenous PI-PLC by coupling to Gaq or Ga11. |
|
| Publications: |
1 |
Organism: |
Chlorocebus Aethiops |
4.0
GNA11
- 
- 