| + |
PRKACA | up-regulates activity 
phosphorylation
|
ETV5 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-111239 |
Ser367 |
PPYQRRGsLQLWQFL |
Homo sapiens |
RK-13 Cell |
| pmid |
sentence |
| 11682477 |
We further show that the increase in erm transcriptional activity after pka phosphorylation is closely correlated with a drastic reduction in the dna binding of the transcription factor. These results indicate that the phosphorylation of erm by pka is involved in erm-mediated transcription and suggest that the activation of erm is probably related to conformational changes. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NFIX | down-regulates quantity 
transcriptional regulation
|
ETV5 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268886 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
By integrating transcriptomic profiling (RNA-seq) of Nfia- and Nfix-deficient GNPs with epigenomic profiling (ChIP-seq against NFIA, NFIB and NFIX, and DNase I hypersensitivity assays), we reveal that these transcription factors share a large set of potential transcriptional targets, suggestive of complementary roles for these NFI family members in promoting neural development |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIB | down-regulates quantity
transcriptional regulation
|
ETV5 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268880 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
By integrating transcriptomic profiling (RNA-seq) of Nfia- and Nfix-deficient GNPs with epigenomic profiling (ChIP-seq against NFIA, NFIB and NFIX, and DNase I hypersensitivity assays), we reveal that these transcription factors share a large set of potential transcriptional targets, suggestive of complementary roles for these NFI family members in promoting neural development |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIA | down-regulates quantity
transcriptional regulation
|
ETV5 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268874 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
By integrating transcriptomic profiling (RNA-seq) of Nfia- and Nfix-deficient GNPs with epigenomic profiling (ChIP-seq against NFIA, NFIB and NFIX, and DNase I hypersensitivity assays), we reveal that these transcription factors share a large set of potential transcriptional targets, suggestive of complementary roles for these NFI family members in promoting neural development |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
UBE2I | down-regulates
sumoylation
|
ETV5 |
0.269 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-135850 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15857832 |
Here we show that erm interacts with the sumo-conjugating enzyme ubc9 and is modified by sumo. We further show that sumo modification of this ets transcription factor affects its ability to activate transcription. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
ETV5
- 
- 