| + |
NFIX | up-regulates quantity 
transcriptional regulation
|
EPHA5 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268909 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
For example, within the NFI targetome, we identified 6 collagen genes, 13 genes encoding potassium channel or glutamate receptor subunits and a range of factors related to axon guidance (e.g. Slit1, Robo1, Epha4, Epha5, Epha8) |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIX | up-regulates quantity
transcriptional regulation
|
NEUROD1 |
0.268 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268904 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
For example, within the NFI targetome, we identified 6 collagen genes, 13 genes encoding potassium channel or glutamate receptor subunits and a range of factors related to axon guidance (e.g. Slit1, Robo1, Epha4, Epha5, Epha8) |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIA | up-regulates quantity
transcriptional regulation
|
NFIX |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268871 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 29106906 |
We report that, in the absence of Nfia or Nfib, there is a marked reduction in the spinal cord expression of NFIX, and that NFIB can transcriptionally activate Nfix expression in vitro. These data demonstrate that NFIX is part of the downstream transcriptional program through which NFIA and NFIB coordinate gliogenesis within the spinal cord. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIB | down-regulates activity 
binding
|
NFIX |
0.429 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-240915 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 9099724 |
Coexpression of NFI-B3 with other isoforms of the NFI-B, -C, and -X family, however, led to a strong reduction of transcriptional activation compared with the expression of these factors alone. NFI-B3 apparently forms heterodimers with other NFI proteins thereby interfering with their function. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NFIX | up-regulates quantity
transcriptional regulation
|
RBFOX3 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268913 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
For example, within the NFI targetome, we identified 6 collagen genes, 13 genes encoding potassium channel or glutamate receptor subunits and a range of factors related to axon guidance (e.g. Slit1, Robo1, Epha4, Epha5, Epha8) |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIX | down-regulates quantity
transcriptional regulation
|
ANOS1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268884 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
By integrating transcriptomic profiling (RNA-seq) of Nfia- and Nfix-deficient GNPs with epigenomic profiling (ChIP-seq against NFIA, NFIB and NFIX, and DNase I hypersensitivity assays), we reveal that these transcription factors share a large set of potential transcriptional targets, suggestive of complementary roles for these NFI family members in promoting neural development |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIX | up-regulates quantity
transcriptional regulation
|
EPHA4 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268908 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
For example, within the NFI targetome, we identified 6 collagen genes, 13 genes encoding potassium channel or glutamate receptor subunits and a range of factors related to axon guidance (e.g. Slit1, Robo1, Epha4, Epha5, Epha8) |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIX | down-regulates quantity
transcriptional regulation
|
ETV5 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268886 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
By integrating transcriptomic profiling (RNA-seq) of Nfia- and Nfix-deficient GNPs with epigenomic profiling (ChIP-seq against NFIA, NFIB and NFIX, and DNase I hypersensitivity assays), we reveal that these transcription factors share a large set of potential transcriptional targets, suggestive of complementary roles for these NFI family members in promoting neural development |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIX | form complex 
binding
|
PKCtheta/Nfix |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-238016 |
|
|
Mus musculus |
C2C12 Cell |
| pmid |
sentence |
| 20178747 |
In the case of the MCK promoter, Nfix forms a complex with PKC theta that binds, phosphorylates, and activates MEF2A. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIX | down-regulates quantity
transcriptional regulation
|
WNT5A |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268889 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
By integrating transcriptomic profiling (RNA-seq) of Nfia- and Nfix-deficient GNPs with epigenomic profiling (ChIP-seq against NFIA, NFIB and NFIX, and DNase I hypersensitivity assays), we reveal that these transcription factors share a large set of potential transcriptional targets, suggestive of complementary roles for these NFI family members in promoting neural development |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIX | up-regulates quantity
transcriptional regulation
|
SLIT1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268906 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
For example, within the NFI targetome, we identified 6 collagen genes, 13 genes encoding potassium channel or glutamate receptor subunits and a range of factors related to axon guidance (e.g. Slit1, Robo1, Epha4, Epha5, Epha8) |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIX | down-regulates quantity
transcriptional regulation
|
ID3 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268885 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
By integrating transcriptomic profiling (RNA-seq) of Nfia- and Nfix-deficient GNPs with epigenomic profiling (ChIP-seq against NFIA, NFIB and NFIX, and DNase I hypersensitivity assays), we reveal that these transcription factors share a large set of potential transcriptional targets, suggestive of complementary roles for these NFI family members in promoting neural development |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
FOXA1 | up-regulates
binding
|
NFIX |
0.341 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-205082 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24801505 |
Androgen receptor (ar) action throughout prostate development and in maintenance of the prostatic epithelium is partly controlled by interactions between ar and forkhead box (fox) transcription factors, particularly foxa1./ Foxa1 is capable of bringing ar and nfix into proximity, indicating that foxa1 facilitates the ar and nfi interaction by bridging the complex. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Prostate Gland |
| + |
NFIB | up-regulates quantity
transcriptional regulation
|
NFIX |
0.429 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268869 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 29106906 |
We report that, in the absence of Nfia or Nfib, there is a marked reduction in the spinal cord expression of NFIX, and that NFIB can transcriptionally activate Nfix expression in vitro. These data demonstrate that NFIX is part of the downstream transcriptional program through which NFIA and NFIB coordinate gliogenesis within the spinal cord. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268870 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 29106906 |
We report that, in the absence of Nfia or Nfib, there is a marked reduction in the spinal cord expression of NFIX, and that NFIB can transcriptionally activate Nfix expression in vitro. These data demonstrate that NFIX is part of the downstream transcriptional program through which NFIA and NFIB coordinate gliogenesis within the spinal cord. |
|
| Publications: |
2 |
Organism: |
Mus Musculus |
| + |
NFIX | up-regulates quantity
transcriptional regulation
|
EPHA8 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268910 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
For example, within the NFI targetome, we identified 6 collagen genes, 13 genes encoding potassium channel or glutamate receptor subunits and a range of factors related to axon guidance (e.g. Slit1, Robo1, Epha4, Epha5, Epha8) |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIX | down-regulates quantity
transcriptional regulation
|
FOXO6 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268887 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
By integrating transcriptomic profiling (RNA-seq) of Nfia- and Nfix-deficient GNPs with epigenomic profiling (ChIP-seq against NFIA, NFIB and NFIX, and DNase I hypersensitivity assays), we reveal that these transcription factors share a large set of potential transcriptional targets, suggestive of complementary roles for these NFI family members in promoting neural development |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIX | up-regulates quantity
transcriptional regulation
|
ROBO1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268907 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
For example, within the NFI targetome, we identified 6 collagen genes, 13 genes encoding potassium channel or glutamate receptor subunits and a range of factors related to axon guidance (e.g. Slit1, Robo1, Epha4, Epha5, Epha8) |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIX | up-regulates quantity
transcriptional regulation
|
NEUROD4 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268905 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
For example, within the NFI targetome, we identified 6 collagen genes, 13 genes encoding potassium channel or glutamate receptor subunits and a range of factors related to axon guidance (e.g. Slit1, Robo1, Epha4, Epha5, Epha8) |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NFIX | down-regulates quantity
transcriptional regulation
|
GAS6 |
0.205 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268888 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 31838646 |
By integrating transcriptomic profiling (RNA-seq) of Nfia- and Nfix-deficient GNPs with epigenomic profiling (ChIP-seq against NFIA, NFIB and NFIX, and DNase I hypersensitivity assays), we reveal that these transcription factors share a large set of potential transcriptional targets, suggestive of complementary roles for these NFI family members in promoting neural development |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
3.0
NFIX
- 
- 