| + |
MAPK3 | down-regulates
phosphorylation
|
PCYT1A |
0.461 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-134841 |
Ser315 |
GRMLQAIsPKQSPSS |
Homo sapiens |
|
| pmid |
sentence |
| 15788406 |
Oxysterols inhibit phosphatidylcholine synthesis via erk docking and phosphorylation of ctp:phosphocholine cytidylyltransferase. Mutagenesis of ser315 within cctalpha was both required and sufficient to confer significant resistance to 22-hc/9-cis-ra inhibition of ptdcho synthesis. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Lung |
| + |
MAPK1 | down-regulates
phosphorylation
|
PCYT1A |
0.451 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-134837 |
Ser315 |
GRMLQAIsPKQSPSS |
Homo sapiens |
|
| pmid |
sentence |
| 15788406 |
Oxysterols inhibit phosphatidylcholine synthesis via erk docking and phosphorylation of ctp:phosphocholine cytidylyltransferase. Mutagenesis of ser315 within cctalpha was both required and sufficient to confer significant resistance to 22-hc/9-cis-ra inhibition of ptdcho synthesis. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Lung |
| + |
SP1 | up-regulates quantity by expression
transcriptional regulation
|
PCYT1A |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266231 |
|
|
Drosophila melanogaster |
SCHNEIDER-2 Cell |
| pmid |
sentence |
| 10744779 |
Sp1 and Sp3 function as transcriptional activators of the Ctpct promoter |
|
| Publications: |
1 |
Organism: |
Drosophila Melanogaster |
| + |
SP3 | up-regulates quantity by expression
transcriptional regulation
|
PCYT1A |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266232 |
|
|
Drosophila melanogaster |
SCHNEIDER-2 Cell |
| pmid |
sentence |
| 10744779 |
Sp1 and Sp3 function as transcriptional activators of the Ctpct promoter |
|
| Publications: |
1 |
Organism: |
Drosophila Melanogaster |
| + |
Gbeta | down-regulates
phosphorylation
|
PCYT1A |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270028 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15788406 |
Oxysterols inhibit phosphatidylcholine synthesis via erk docking and phosphorylation of ctp:phosphocholine cytidylyltransferase. Mutagenesis of ser315 within cctalpha was both required and sufficient to confer significant resistance to 22-hc/9-cis-ra inhibition of ptdcho synthesis. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Lung |
| + |
SP2 | down-regulates quantity by repression
transcriptional regulation
|
PCYT1A |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266230 |
|
|
Drosophila melanogaster |
SCHNEIDER-2 Cell |
| pmid |
sentence |
| 10744779 |
Sp3 is an activator, and Sp2 a repressor, of the Ctpct promoter in SL2 cells. |
|
| Publications: |
1 |
Organism: |
Drosophila Melanogaster |
| + |
ERK1/2 | down-regulates
phosphorylation
|
PCYT1A |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270151 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15788406 |
Oxysterols inhibit phosphatidylcholine synthesis via erk docking and phosphorylation of ctp:phosphocholine cytidylyltransferase. Mutagenesis of ser315 within cctalpha was both required and sufficient to confer significant resistance to 22-hc/9-cis-ra inhibition of ptdcho synthesis. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Lung |