| + |
MAPK1 |
phosphorylation
|
NUP153 |
0.398 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-188123 |
Ser529 |
SPMFKFSsPIVKSTE |
Homo sapiens |
|
| pmid |
sentence |
| 19767751 |
These results indicate that phosphorylation of nup153 and nup214 by erk strongly reduces their affinity for importin-. nup153 depletion caused a strong inhibition of nuclear accumulation of gfp?importin-beta in both erk-inhibited and erk-activated cells (fig. 8b,c), indicating that nup153 is essential for the efficient importin-beta transport. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-188127 |
Thr388 |
VYFKPSLtPSGEFRK |
Homo sapiens |
|
| pmid |
sentence |
| 19767751 |
These results indicate that phosphorylation of nup153 and nup214 by erk strongly reduces their affinity for importin-. nup153 depletion caused a strong inhibition of nuclear accumulation of gfp?importin-beta in both erk-inhibited and erk-activated cells (fig. 8b,c), indicating that nup153 is essential for the efficient importin-beta transport. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
MAPK3 |
phosphorylation
|
NUP153 |
0.401 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-188143 |
Ser529 |
SPMFKFSsPIVKSTE |
Homo sapiens |
|
| pmid |
sentence |
| 19767751 |
These results indicate that phosphorylation of nup153 and nup214 by erk strongly reduces their affinity for importin-. nup153 depletion caused a strong inhibition of nuclear accumulation of gfp?importin-beta in both erk-inhibited and erk-activated cells (fig. 8b,c), indicating that nup153 is essential for the efficient importin-beta transport. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-188147 |
Thr388 |
VYFKPSLtPSGEFRK |
Homo sapiens |
|
| pmid |
sentence |
| 19767751 |
These results indicate that phosphorylation of nup153 and nup214 by erk strongly reduces their affinity for importin-. nup153 depletion caused a strong inhibition of nuclear accumulation of gfp?importin-beta in both erk-inhibited and erk-activated cells (fig. 8b,c), indicating that nup153 is essential for the efficient importin-beta transport. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
ERK1/2 |
phosphorylation
|
NUP153 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270159 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 19767751 |
These results indicate that phosphorylation of nup153 and nup214 by erk strongly reduces their affinity for importin-. nup153 depletion caused a strong inhibition of nuclear accumulation of gfp?importin-beta in both erk-inhibited and erk-activated cells (fig. 8b,c), indicating that nup153 is essential for the efficient importin-beta transport. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SUN1 | up-regulates activity 
binding
|
NUP153 |
0.449 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263294 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 28831067 |
The NXF1:NXT1 complex and NUP153 interact with the amino terminus of SUN1 |In analogy to a proposal made by Chang et al.4, Nesprins could help anchoring SUN1 near the NPC to enable it to fulfill its task in mRNA export. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
Gbeta |
phosphorylation
|
NUP153 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270044 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 19767751 |
These results indicate that phosphorylation of nup153 and nup214 by erk strongly reduces their affinity for importin-. nup153 depletion caused a strong inhibition of nuclear accumulation of gfp?importin-beta in both erk-inhibited and erk-activated cells (fig. 8b,c), indicating that nup153 is essential for the efficient importin-beta transport. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TNPO1 | up-regulates activity
relocalization
|
NUP153 |
0.518 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262100 |
|
|
|
|
| pmid |
sentence |
| 29970603 |
TNPO1 only mediates the nuclear import of a subset of proteins.|Among TNPO1 cargos, the most extensively characterized is the RNA binding protein heterogeneous nuclear ribonucleoprotein 1 (hnRNPA1) (27), which functions in several processes including mRNA biogenesis and promotion of transcription factor activity (28–30). NPC protein NUP153 is also a target for TNPO1-mediated nuclear import |
|
| Publications: |
1 |
| + |
NUP153 | form complex 
binding
|
NPC |
0.731 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262069 |
|
|
|
|
| pmid |
sentence |
| 27016207 |
The protein inventory of the NPC has been studied for a very diverse set of eukaryotes, including trypanosomes, fungi, plants, animals, and humans [4], [5], [6], [7], [8], [9]. In all cases, about 30 different Nups were found (Fig. 2). |
|
| Publications: |
1 |
3.0
NUP153
- 
- 