3.0
Summary
| Name |  MXI1View Modifications |
| Full Name | Max-interacting protein 1 |
| Synonyms | Max interactor 1, Class C basic helix-loop-helix protein 11, bHLHc11 | BHLHC11 |
| Primary ID | P50539 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | RPS6KB1 | down-regulates activity 
phosphorylation
|
MXI1 | |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | SMC3 | down-regulates activity
binding
|
MXI1 | 0.411 |
| Publications: | 1 | Organism: | Chlorocebus Aethiops | |
| + | MAX | up-regulates activity 
binding
|
MXI1 | 0.572 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | MXI1 | down-regulates quantity by repression
transcriptional regulation
|
CCNB1 | 0.269 |
| Publications: | 1 | Organism: | Homo Sapiens | |