3.0
Summary
| Name |  ARHGDIBView Modifications |
| Full Name | Rho GDP-dissociation inhibitor 2 |
| Synonyms | Rho GDI 2, Ly-GDI, Rho-GDI beta | GDIA2, GDID4, RAP1GN1 |
| Primary ID | P52566 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:8356058, PubMed:7512369). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PRKCA | down-regulates 
phosphorylation
|
ARHGDIB | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | SRC |
phosphorylation
|
ARHGDIB | 0.405 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | RNF128 | up-regulates quantity by stabilization 
polyubiquitination
|
ARHGDIB | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |