+ |
EFNA5 | up-regulates
binding
|
EPHA5 |
0.892 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-52476 |
|
|
Homo sapiens |
|
pmid |
sentence |
9330863 |
Receptors of the epha group preferentially interact with glycosylphosphatidylinositol (gpi)-linked ligands (of the ephrin-a subclass, which comprises five ligands), while receptors of the ephb group preferentially interact with transmembrane ligands (of the ephrin-b subclass, which comprises three ligands) (table 1). In either case, binding of a ligand results in eph receptor autophosphorylation on tyrosine residues and activation of the kinase activity of the eph receptor |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
EFNA2 | up-regulates
binding
|
EPHA5 |
0.812 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-65416 |
|
|
Homo sapiens |
|
pmid |
sentence |
10072375 |
Ephrin-a ligands (named ephrin-a1_ephrin-a5) are anchored in the plasma membrane through a gpi-linkage, and each can bind any of the epha subclass of receptors (epha1_epha8) |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
EFNA3 | up-regulates
binding
|
EPHA5 |
0.811 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-52381 |
|
|
Homo sapiens |
|
pmid |
sentence |
9330863 |
Receptors of the epha group preferentially interact with glycosylphosphatidylinositol (gpi)-linked ligands (of the ephrin-a subclass, which comprises five ligands), while receptors of the ephb group preferentially interact with transmembrane ligands (of the ephrin-b subclass, which comprises three ligands) (table 1). In either case, binding of a ligand results in eph receptor autophosphorylation on tyrosine residues and activation of the kinase activity of the eph receptor |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
EFNA1 | up-regulates
binding
|
EPHA5 |
0.804 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-56910 |
|
|
Homo sapiens |
|
pmid |
sentence |
9576626 |
Ephrin-a1 binds and activates the tyrosine kinase activity of eph-a2, and has a dissociation constant of 20_30 nm. ephrin-a1 interacts with all the other epha subclass receptors as well, although with different affinity |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
NFIA | up-regulates quantity
transcriptional regulation
|
EPHA5 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-268895 |
|
|
Mus musculus |
|
pmid |
sentence |
31838646 |
For example, within the NFI targetome, we identified 6 collagen genes, 13 genes encoding potassium channel or glutamate receptor subunits and a range of factors related to axon guidance (e.g. Slit1, Robo1, Epha4, Epha5, Epha8) |
|
Publications: |
1 |
Organism: |
Mus Musculus |
+ |
NFIB | up-regulates quantity
transcriptional regulation
|
EPHA5 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-268902 |
|
|
Mus musculus |
|
pmid |
sentence |
31838646 |
For example, within the NFI targetome, we identified 6 collagen genes, 13 genes encoding potassium channel or glutamate receptor subunits and a range of factors related to axon guidance (e.g. Slit1, Robo1, Epha4, Epha5, Epha8) |
|
Publications: |
1 |
Organism: |
Mus Musculus |
+ |
EFNA4 | up-regulates
binding
|
EPHA5 |
0.804 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-52430 |
|
|
Homo sapiens |
|
pmid |
sentence |
9330863 |
Receptors of the epha group preferentially interact with glycosylphosphatidylinositol (gpi)-linked ligands (of the ephrin-a subclass, which comprises five ligands), while receptors of the ephb group preferentially interact with transmembrane ligands (of the ephrin-b subclass, which comprises three ligands) (table 1). In either case, binding of a ligand results in eph receptor autophosphorylation on tyrosine residues and activation of the kinase activity of the eph receptor |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
NFIX | up-regulates quantity
transcriptional regulation
|
EPHA5 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-268909 |
|
|
Mus musculus |
|
pmid |
sentence |
31838646 |
For example, within the NFI targetome, we identified 6 collagen genes, 13 genes encoding potassium channel or glutamate receptor subunits and a range of factors related to axon guidance (e.g. Slit1, Robo1, Epha4, Epha5, Epha8) |
|
Publications: |
1 |
Organism: |
Mus Musculus |