| + |
CTBP2 | down-regulates quantity by repression 
transcriptional regulation
|
CDH1 |
0.39 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261578 |
|
|
Homo sapiens |
HEK-293T Cell |
| pmid |
sentence |
| 21315774 |
Overexpression of the CtBP2 protein enhanced the repression activity of the E-cadherin promoter in a dose-dependent manner, whereas overexpression of ataxin-1 increased the activity of the E-cadherin promoter in a dose-dependent manner |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
STUB1 | down-regulates quantity by destabilization
ubiquitination
|
CTBP2 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-278722 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23410750 |
Our data showed that CHIP depletion resulted in up-regulation of the steady-state level of CtBP2 ( Fig. 1 B) and that CHIP ubiquitinated CtBP2 for proteasomal degradation ( Fig. 3 A). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
KLF8 | up-regulates activity 
binding
|
CTBP2 |
0.544 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-236962 |
|
|
Mus musculus |
NIH-3T3 Cell |
| pmid |
sentence |
| 10756197 |
Here we report the characterisation of KLF8/ZNF741/BKLF3 (KLF8). We demonstrate that this protein is able to bind CACCC-boxes in DNA and can repress gene expression by associating with CtBP co-repressors. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
3.0
CTBP2
- 
- 