Name	WNT3
Full Name	Proto-oncogene Wnt-3
Synonyms	Proto-oncogene Int-4 homolog \| INT4
Primary ID	P56703
Links	- -
Type	protein
Relations	4
Pathways	GPCR_HCC
Function	Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:26902720). Required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis. Required for normal formation of the apical ectodermal ridge (By similarity). Required for normal embryonic development, and especially for limb development (PubMed:14872406).