Summary

Name FGF12
Full Name Fibroblast growth factor 12
Synonyms FGF-12, Fibroblast growth factor homologous factor 1, FHF-1, Myocyte-activating factor | FGF12B, FHF1
Primary ID P61328
Links - -
Type protein
Relations 9
Function Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity. Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation.

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png binding SCN3A 0.237
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding SCN4A 0.258
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding SCN11A 0.268
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding SCN2A 0.315
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding SCN1A 0.394
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding SCN10A 0.307
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding SCN9A 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding SCN8A 0.323
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding SCN5A 0.596
Publications: 1 Organism: Homo Sapiens
Tissue: Cardiac Muscle