Summary

Name HAMP
Full Name Hepcidin
Synonyms Liver-expressed antimicrobial peptide 1, LEAP-1, Putative liver tumor regressor, PLTR | HEPC, LEAP1
Primary ID P81172
Links - -
Type protein
Relations 3
Function Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HAMP 0.439
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HAMP 0.302
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HAMP 0.2
Publications: 1 Organism: Homo Sapiens