+ |
PRKG1 | down-regulates
phosphorylation
|
TRPC3 |
0.417 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-142953 |
Ser251 |
KNDYRKLsMQCKDFV |
Homo sapiens |
|
pmid |
sentence |
16331690 |
There are two known phosphorylation-mediated inactivation mechanisms for trpc3 channels. Protein kinase g (pkg) inactivates trpc3 by direct phosphorylation on thr-11 and ser-263 of the trpc3 proteins, and protein kinase c (pkc) inactivates trpc3 by phosphorylation on ser-712. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-122978 |
Ser251 |
KNDYRKLsMQCKDFV |
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
14983059 |
There are two known phosphorylation-mediated inactivation mechanisms for trpc3 channels. Protein kinase g (pkg) inactivates trpc3 by direct phosphorylation on thr-11 and ser-263 of the trpc3 proteins, and protein kinase c (pkc) inactivates trpc3 by phosphorylation on ser-712. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-142961 |
Ser251 |
KNDYRKLsMQCKDFV |
Homo sapiens |
|
pmid |
sentence |
16331690 |
The present study demonstrates that human trpc3 expressed in hek293 cells forms store-operated ca2+ influx channels, the activity of which is inhibited by pkg. The inhibition is due to a direct phosphorylation of pkg on trpc3 channels at position t11 and s263. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-142964 |
|
|
Homo sapiens |
|
pmid |
sentence |
16331690 |
The present study demonstrates that human trpc3 expressed in hek293 cells forms store-operated ca2+ influx channels, the activity of which is inhibited by pkg. The inhibition is due to a direct phosphorylation of pkg on trpc3 channels at position t11 and s263. |
|
Publications: |
4 |
Organism: |
Homo Sapiens |
+ |
PRKCA | down-regulates
phosphorylation
|
TRPC3 |
0.354 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-142945 |
Ser703 |
SLVPSPKsFVYFIMR |
Homo sapiens |
|
pmid |
sentence |
16331690 |
There are two known phosphorylation-mediated inactivation mechanisms for trpc3 channels. Protein kinase g (pkg) inactivates trpc3 by direct phosphorylation on thr-11 and ser-263 of the trpc3 proteins, and protein kinase c (pkc) inactivates trpc3 by phosphorylation on ser-712. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-130269 |
Ser703 |
SLVPSPKsFVYFIMR |
Homo sapiens |
|
pmid |
sentence |
15533987 |
There are two known phosphorylation-mediated inactivation mechanisms for trpc3 channels. Protein kinase g (pkg) inactivates trpc3 by direct phosphorylation on thr-11 and ser-263 of the trpc3 proteins, and protein kinase c (pkc) inactivates trpc3 by phosphorylation on ser-712. |
|
Publications: |
2 |
Organism: |
Homo Sapiens |
Tissue: |
Kidney |
+ |
PRKG1 | down-regulates
phosphorylation
|
TRPC3 (isoform 3) |
0.417 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-142957 |
Thr11 |
SPSLRRMtVMREKGR |
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
16331690 |
The present study demonstrates that human trpc3 expressed in hek293 cells forms store-operated ca2+ influx channels, the activity of which is inhibited by pkg. The inhibition is due to a direct phosphorylation of pkg on trpc3 channels at position t11 and s263. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |