Summary

Name TRPC3
Full Name Short transient receptor potential channel 3
Synonyms TrpC3, Transient receptor protein 3, TRP-3, hTrp-3, hTrp3 | TRP3
Primary ID Q13507
Links - -
Type protein
Relations 7
Function Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5-triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion.

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png phosphorylation TRPC3 0.417
Publications: 4 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation TRPC3 0.354
Publications: 2 Organism: Homo Sapiens
Tissue: Kidney
+ down-regulates img/direct_inhibition.png phosphorylation TRPC3 (isoform 3) 0.417
Publications: 1 Organism: Homo Sapiens