| + |
CHEK2 | down-regulates
phosphorylation
|
RASGRF1 |
0.403 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-150843 |
Ser287 |
PITHDDVsSIFLNSE |
Homo sapiens |
|
| pmid |
sentence |
| 17110335 |
During interphase, cdc25 is inhibited by ser287 phosphorylation (xenopus cdc25;ser 216 in human cdc25c) and this inhibitory phosphorylation is maintained by dna-responsive checkpoints / s287 is targeted by many kinases, including chk1, chk2, ctak-1, pka, p38 and mapkap kinase-2 suggesting that phosphorylation of this site may integrate multiple signaling inputs. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PRKACA | up-regulates
phosphorylation
|
RASGRF1 |
0.518 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-73202 |
Ser927 |
KEKYRRMsLASAGFP |
Homo sapiens |
Neuron |
| pmid |
sentence |
| 10601308 |
Phosphorylation of serine 916 of ras-grf1 contributes to the activation of exchange factor activity by muscarinic receptors. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SRC | down-regulates activity
phosphorylation
|
RASGRF1 |
0.471 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280133 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24597981 |
These proximal Src kinases could potentially directly or indirectly phosphorylate Rasgrf-1 upon BCR activation and thereby further increase its GEF activity. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |