| + |
EIF2B1 | up-regulates activity 
guanine nucleotide exchange factor
|
EIF2S1 |
0.823 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269124 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15054402 |
EIF2B converts the protein synthesis initiation factor 2 (eIF2) from an inactive GDP-bound form to an active eIF2-GTP complex owing to its guanine nucleotide exchange factor (GEF) activity. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Initiation of Translation |
| + |
GSK3B | down-regulates 
binding
|
EIF2B1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-175436 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21798082 |
Akt also promotes protein synthesis by phosphorylating and inactivating gsk3b, thus releasing the gsk3b-dependent inhibition of the eukariotic translation initiation factor 2b (eif2b). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
EIF2B1 | up-regulates activity
guanine nucleotide exchange factor
|
EIF2S2 |
0.77 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269129 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15054402 |
EIF2B converts the protein synthesis initiation factor 2 (eIF2) from an inactive GDP-bound form to an active eIF2-GTP complex owing to its guanine nucleotide exchange factor (GEF) activity. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
EIF2B1 | up-regulates activity
guanine nucleotide exchange factor
|
EIF2S3 |
0.681 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269134 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15054402 |
EIF2B converts the protein synthesis initiation factor 2 (eIF2) from an inactive GDP-bound form to an active eIF2-GTP complex owing to its guanine nucleotide exchange factor (GEF) activity. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
EIF2B1 | up-regulates activity
guanine nucleotide exchange factor
|
Ternary_GTP_eIF2_tRNA_complex |
0.758 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269139 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15054402 |
EIF2B converts the protein synthesis initiation factor 2 (eIF2) from an inactive GDP-bound form to an active eIF2-GTP complex owing to its guanine nucleotide exchange factor (GEF) activity. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Initiation of Translation |
3.0
EIF2B1
- 
- 