| + |
PRKCD | up-regulates 
phosphorylation
|
ELAVL1 |
0.36 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-163524 |
Ser221 |
QAQRFRFsPMGVDHM |
Homo sapiens |
|
| pmid |
sentence |
| 20086103 |
Tandem phosphorylation of serines 221 and 318 by protein kinase cdelta coordinates mrna binding and nucleocytoplasmic shuttling of hurstabilization of mrna by the ubiquitous rna binding protein human antigen r (hur), a member of the embryonic lethal abnormal vision (elav) protein family, requires canonical binding to au-rich element (are)-bearing target mrna and export of nuclear hur-mrna complexes to the cytoplasm. In human mesangial cells (hmc) both processes are induced by angiotensin ii (angii) via protein kinase cdelta (pkcdelta)-triggered serine phosphorylation of hur. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-163528 |
Ser318 |
GDKILQVsFKTNKSH |
Homo sapiens |
|
| pmid |
sentence |
| 20086103 |
Tandem phosphorylation of serines 221 and 318 by protein kinase cdelta coordinates mrna binding and nucleocytoplasmic shuttling of hurstabilization of mrna by the ubiquitous rna binding protein human antigen r (hur), a member of the embryonic lethal abnormal vision (elav) protein family, requires canonical binding to au-rich element (are)-bearing target mrna and export of nuclear hur-mrna complexes to the cytoplasm. In human mesangial cells (hmc) both processes are induced by angiotensin ii (angii) via protein kinase cdelta (pkcdelta)-triggered serine phosphorylation of hur. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
MAPK14 | up-regulates
phosphorylation
|
ELAVL1 |
0.22 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-186135 |
Thr118 |
SGLPRTMtQKDVEDM |
Homo sapiens |
|
| pmid |
sentence |
| 19528229 |
P38 mapk phosphorylates the mrna binding protein hur on thr118, which results in cytoplasmic accumulation of hur and its enhanced binding to the p21cip1 mrna. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-186138 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 19528229 |
P38 mapk phosphorylates the mrna binding protein hur on thr118, which results in cytoplasmic accumulation of hur and its enhanced binding to the p21cip1 mrna. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
MAPKAPK2 | up-regulates
phosphorylation
|
ELAVL1 |
0.31 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-166622 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20626350 |
Mk2 and mk3 participate in the control of gene expression mostly at the post-transcriptional level, by phosphorylating the are-binding proteins ttp and hur, and by regulating eef2k |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
ELAVL1
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